2024 Jama cardiology - August 1, 2017. Treatment of Cholesterol in 2017. Harlan M. Krumholz, MD, SM 1,2. Author Affiliations Article Information. 1 Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine. 2 The Center for Outcomes Research and Evaluation, Yale–New Haven Health, New Haven, Connecticut.

 
 Corresponding Author: Sadiya S. Khan, MD, MS, Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, 680 N Lake Shore Dr, 14-002, Chicago, IL 60611 (s-khan-1@northwestern.edu). . Jama cardiology

Key Points. Question Is there an association between normal systolic blood pressure values as currently defined and atherosclerotic cardiovascular disease among persons without traditional cardiovascular disease risk factors?. Findings In this cohort study including 1457 participants without atherosclerotic cardiovascular disease, beginning with a systolic …Key Points. Question Is level of high-density lipoprotein cholesterol (HDL-C) associated with an increased fracture risk in healthy older adults?. Findings In this cohort study of 16 262 community-dwelling healthy participants 70 years and older, 1659 participants experienced at least 1 fracture over a median follow-up of 4 years. In the fully adjusted model, each 1 …Key Points. Question What are the characteristics and outcomes of patients with heart transplant who are infected with coronavirus disease 2019 (COVID-19)?. Findings In this case series of 28 patients who had received heart transplant in a large academic center, the case fatality rate among patients infected with COVID-19 was 25%. . Cardiovascular comorbidities …4 Associate Editor, JAMA Cardiology. 5 Duke University School of Medicine, Durham, North Carolina. 6 Deputy Editor for Statistics, JAMA Cardiology. 7 Department of Pharmacological and Biomolecular Sciences, University of …JAMA Cardiology. Full Text. Leaving the broken system the way it is, that’s not a solution. 1. Barack Obama. It must be recognized that our current health care delivery system has failed to adequately treat 2 of our nation’s top cardiovascular risk factors: high blood pressure (BP) and hyperlipidemia. Heidenreich PA , Bozkurt B , Aguilar D , et al. 2022 AHA/ACC/HFSA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts …Disclaimer: Dr Thomas is the Assistant Editor for Statistics of JAMA Cardiology, Dr Hernandez is an Associate Editor for JAMA Cardiology, and Dr Fonarow is the Associate Editor of Health Care Quality and Guidelines for JAMA Cardiology, but they were not involved in any of the decisions regarding review of the manuscript or its acceptance.JAMA Cardiology is an international peer-reviewed journal and the definitive journal for clinical investigators, clinicians, and trainees in cardiovascular medicine … Das SR , Everett BM , Birtcher KK , et al. 2018 ACC expert consensus decision pathway on novel therapies for cardiovascular risk reduction in patients with type 2 diabetes and atherosclerotic cardiovascular disease: a report of the American College of Cardiology task force on expert consensus decision pathways. JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Key Points. Question What are the cardiac complications associated with the emerging outbreak of coronavirus disease 2019 (COVID-19)?. Findings In this case report, an otherwise healthy 53-year-old patient developed acute myopericarditis with systolic dysfunction confirmed on cardiac magnetic resonance imaging a week after onset of fever and dry cough …With the exception of the flu pandemic years of 1918-1920, heart disease (HD) has been the leading cause of death in the United States since 1910, 1 with cancer and stroke among the 5 leading causes of death every year since 1924. 2 From 2000 to 2010, age-adjusted mortality decreased 30% for HD and 36% for stroke, but cancer mortality …In this Viewpoint, JAMA Cardiology editors review the journal's more inportant articles advancing the scientific understanding of COVID-19 and the heart in the first 6 months of the pandemic, including evidence of …JAMA Cardiology. Coronavirus disease 2019 (COVID-19) is associated with significant mortality and morbidity, including adverse cardiovascular sequelae. 1 As public health policy begins to guide the resumption of recreational and competitive sport, clinicians are charged with determining when competitive athletes and highly active individuals ...JAMA Cardiology. Key Points. Question When does the clinical benefit of dapagliflozin emerge in patients with heart failure with reduced ejection fraction, and what is the magnitude as a function of proximity to prior heart failure hospitalization?Given the evidence of the effectiveness of statins in reducing atherosclerotic cardiovascular disease (ASCVD) events and mortality, the 2013 American College of Cardiology (ACC) and the American Heart Association (AHA) cholesterol treatment guidelines recommended high-intensity statins for most patients with ASCVD. 1 The recently updated 2018 cholesterol …Jan 1, 2021 · Myocarditis is a significant cause of sudden cardiac death in competitive athletes and can occur with normal ventricular function. 1 Recent studies have raised concerns of myocardial inflammation after recovery from coronavirus disease 2019 (COVID-19), even in asymptomatic or mildly symptomatic patients. 2 Our objective was to investigate the use of cardiac magnetic resonance (CMR) imaging in ... DOI: 10.1001/jamacardio.2021.3055. Abstract. Importance: The density of atherosclerotic plaque forms the basis for categorizing calcified and noncalcified …Key Points. Question What are the efficacy and safety of omecamtiv mecarbil for the treatment of patients with severe heart failure (HF)?. Finding In this post hoc analysis of data from 8232 patients with symptomatic HF enrolled in the Global Approach to Lowering Adverse Cardiac Outcomes Through Improving Contractility in Heart Failure …JAMA Cardiology, Chicago, Illinois. 57,031 likes · 154 talking about this · 9 were here. JAMA Cardiology is a member of the JAMA Network, a consortium of... This secondary analysis of a randomized clinical trial investigates the association between plasma levels of eicosapentaenoic acid and docosahexaenoic acid and cardiovascular outcomes in a trial of ω-3 fatty acids compared with corn oil placebo. Disclaimer: Dr Sabatine is Deputy Editor of JAMA Cardiology, but he was not involved in any of the decisions regarding review of the manuscript or its acceptance. References 1. Beltrán-Sánchez H , Harhay MO , Harhay MM , McElligott S . Prevalence and trends of metabolic syndrome in the adult U.S. population, 1999-2010.Importance Previous studies of basic cardiopulmonary resuscitation (CPR) indicate that both chest compression rate (CCR) and chest compression depth (CCD) each are associated with survival probability after out-of-hospital cardiac arrest. However, an optimal CCR-CCD combination has yet to be identified, particularly with respect to age, …Key Points. Question Is high-intensity interval training (HIIT) superior to moderate-intensity continuous training (MICT) for improving cardiorespiratory fitness during a 4-week hospital-based cardiac rehabilitation program and long-term with home-based training over 12 months?. Findings In this randomized clinical trial including 93 participants, …Beneficial associations of low and large doses of leisure time physical activity with all-cause, cardiovascular disease and cancer mortality: a national cohort study of 88,140 US adults. Br J Sports Med. 2019;53 (22):1405-1411. doi: 10.1136/bjsports-2018 …Key Points. Question Does tafamidis, 80 mg, affect cardiac function in patients with transthyretin amyloid cardiomyopathy?. Findings In this post hoc analysis of the randomized Tafamidis in Transthyretin Cardiomyopathy Clinical Trial including 441 patients, over 30 months, there was less pronounced worsening of left ventricular (LV) stroke volume, LV …Disclaimer: Dr Fonarow is Associate Section Editor of JAMA Cardiology, but he was not involved in any of the decisions regarding review of the manuscript or its acceptance. Meeting Presentation: This paper was presented at the American College of Cardiology 23rd Annual Scientific Session and Expo; March 4, 2023; New Orleans, Louisiana.JAMA Cardiology. Editor's Comment. A Brief Window to Rethink Emergency Care. Melinda B. Buntin, PhD. JAMA Health Forum. We are in the midst of the coronavirus disease 2019 (COVID-19) pandemic and, as many clinicians across the globe, we are seeing firsthand the pain and death caused by COVID-19.JAMA Cardiology, Chicago, Illinois. 57,031 likes · 154 talking about this · 9 were here. JAMA Cardiology is a member of the JAMA Network, a consortium of...JAMA Cardiology. JAMA Guide to Statistics and Methods. Overlap Weighting—A Propensity Score Method That Mimics Attributes of a Randomized Clinical Trial. Laine E. Thomas, PhD; Fan Li, PhD; Michael J. Pencina, PhD. JAMA. Original Investigation. Association of ACEI or ARB Use With COVID-19 Diagnosis and Mortality.In this issue of JAMA Cardiology, Felker et al 3 not only provide an important statement about the potential benefits and risks of omecamtiv mecarbil therapy but, more importantly, provide a clinically evident demarcation of a potentially new stage of HF, specifically patients with HFrEF who are receiving effective guideline-directed medical ...JAMA Cardiology. Coronavirus disease 2019 (COVID-19) is associated with significant mortality and morbidity, including adverse cardiovascular sequelae. 1 As public health policy begins to guide the resumption of recreational and competitive sport, clinicians are charged with determining when competitive athletes and highly active individuals ...JAMA Cardiology. Key Points. Question Is COVID-19 vaccination linked to the occurrence of myocarditis? Findings In this study of 7 patients with acute myocarditis, 4 occurred within 5 days of COVID-19 vaccination between February 1 and April 30, 2021. All 4 ...The 2022 American Heart Association/American College of Cardiology/Heart Failure Society of America Guideline for the Management of Heart Failure recommends the use of cardiac biomarkers, namely natriuretic peptides and cardiac troponins, for HF classification. 4 Within this framework, ambulatory patients with elevated levels of NT …JAMA Cardiology. Key Points. Question What is the optimal target for reduction of systolic blood pressure among patients with hypertension? Findings In this systematic review and network meta-analysis of 42 trials, including 144 220 patients, linear ...Importance Cardiovascular disease is a leading cause of morbidity in cancer survivors, which makes strategies aimed at mitigating cardiovascular risk a subject of major contemporary importance.. Objective To assess whether a center-based cardiac rehabilitation (CBCR) framework compared with usual care encompassing community-based exercise training … JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Key Points. Question In patients diagnosed with atrial fibrillation before 66 years of age, what is the prevalence of disease-associated variants in susceptibility genes for inherited cardiomyopathy and arrhythmia syndromes?. Findings In this cohort study, among 1293 participants who underwent whole genome sequencing, disease-associated rare …Importance Previous studies of basic cardiopulmonary resuscitation (CPR) indicate that both chest compression rate (CCR) and chest compression depth (CCD) each are associated with survival probability after out-of-hospital cardiac arrest. However, an optimal CCR-CCD combination has yet to be identified, particularly with respect to age, …Serum creatinine at enrollment before cardiac catheterization was obtained from routine clinic visits or hospitalizations within the Emory Healthcare system. The eGFR (milliliter per minute per 1.73 m 2 ) was computed using the Chronic Kidney Disease Epidemiology Collaboration equation. 16 Medications were obtained by self-report and …PMID: 32730619. PMCID: PMC7385689. DOI: 10.1001/jamacardio.2020.3557. Abstract. Importance: Coronavirus disease 2019 …JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts … JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Training and credentialing guidelines are inconsistent across medical fields, with cardiology requiring 150 studies performed and 300 interpreted before independent practice 23 while the American College of Emergency Physicians allows as few as 25 cardiac studies for competence. 24 An unintended consequence of varying training …Two articles published in JAMA Cardiology from 2 academic hospitals in Wuhan, China, the epicenter of the COVID-19 pandemic, 10,11 support these concepts while also providing novel insights into the incidence and consequences of myocardial injury associated with SARS-CoV-2.JAMA Network is a consortium of peer-reviewed medical publications that includes JAMA® and the JAMA Network journals. JAMA Cardiology does not hold itself responsible for statements made by any contributor. All articles published, including opinion articles, represent the views of the authors and do not reflect the policy of the Journal, the ... The daily doses of EPA varied from 226 to 1800 mg/day, and DHA varied from 0 to 1700 mg/day. The mean duration of treatment in individual trials varied from 1.0 year to 6.2 years (weighted mean, 4.4 years). Of the 77 917 participants, 47 803 (61.4%) were men, and the mean age at entry was 64 years. JAMA Cardiology. In our annual review of JAMA Cardiology, I am pleased to report that 2022 marked another year of steady growth in publishing original …Preoperative cardiac stress testing is used to assess cardiac risk in patients scheduled for noncardiac surgery. 1-4 The American College of Cardiology and American Heart Association (ACC/AHA) practice guidelines for perioperative cardiovascular evaluation for noncardiac surgery aim to improve the effectiveness of perioperative care, optimize ...All results were obtained through meta-analysis among 3 cohorts. Model 1 was adjusted by age and sex at the time of blood sample collection; model 2 was adjusted by age, sex, body mass index (BMI), smoking status, and physical activity at the time of blood sample collection; and model 3 was adjusted by age, sex, BMI, smoking status, …JAMA Cardiology JAMA Cardiol. 2022 Jul 1;7(7):662. doi: 10.1001/jamacardio.2021.4296. PMID: 35829713 DOI: …Key Points. Question Do contemporary machine learning methods improve prediction of in-hospital death after hospitalization for acute myocardial infarction (AMI)?. Findings In this cohort study of 755 402 patients with AMI in a nationwide registry, machine learning models that used the same data inputs as logistic regression were not associated with …This analysis of pooled data from 2 randomized clinical trials evaluates the 5-year incidence, clinical outcomes, and predictors of hemodynamic structural valve deterioration in patients undergoing self-expanding transcatheter aortic valve implantation or surgery.Jan 14, 2021 · Thirty of 789 athletes (3.8%) had abnormal cardiac screening test results necessitating additional evaluation and downstream testing; 5 athletes (0.6%) were detected to have findings raising concern for COVID-19–associated inflammatory heart disease that resulted in restriction from sport participation per American Heart Association (AHA)/American College of Cardiology (ACC) guidelines. 10 ... Key Points. Question Does tafamidis, 80 mg, affect cardiac function in patients with transthyretin amyloid cardiomyopathy?. Findings In this post hoc analysis of the randomized Tafamidis in Transthyretin Cardiomyopathy Clinical Trial including 441 patients, over 30 months, there was less pronounced worsening of left ventricular (LV) stroke volume, LV …In this issue of JAMA Cardiology, Liu et al 2 provide important new data from 2 secondary prevention samples (UK Biobank, N = 14 478; Emory Cardiovascular Biobank, N = 5467). The prevalence of very high HDL-C (>80 mg/dL) was low in both samples (<2%) and comprised a higher proportion of women and those reporting frequent alcohol use; low ...DOI: 10.1001/jamacardio.2021.3055. Abstract. Importance: The density of atherosclerotic plaque forms the basis for categorizing calcified and noncalcified … JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JAMA Cardiology. Medical News & Perspectives. Highlights From the American Heart Association’s Scientific Sessions—ApoB as a Risk Marker, an Oral PCSK9 Inhibitor, Aspirin and Dementia, and More. Jennifer Abbasi. …10.1001/jamacardio.2018.0022. . Abstract. . Importance: Prior studies have demonstrated lower all-cause mortality in individuals who are overweight …JAMA Cardiology. Key Points. Question Can readily available electrocardiogram (ECG) data be used to train a high-performing convolutional neural network (CNN) across a large …JAMA Cardiology. In our annual review of JAMA Cardiology, I am pleased to report that 2022 marked another year of steady growth in publishing original …JAMA Cardiology. Full Text. Abstract Importance Familial hypercholesterolemia (FH) is an underdiagnosed and undertreated genetic disorder that leads to premature morbidity and mortality due to atherosclerotic cardiovascular disease. Familial hypercholesterolemia affects 1 in 200 to 250 people around the world of every race and ethnicity.Key Points. Question Are accelerometer-measured physical activity (PA) and sedentary behavior associated with incident heart failure in older women?. Findings In this cohort study of 5951 women aged 63 to 99 years, usual daily light PA, moderate to vigorous PA, and steps per day were inversely associated, and total sedentary time positively …Key Points. Question Is patient sex associated with differences in clinical outcomes of pulsed field ablation (PFA) for the treatment of patients with atrial fibrillation (AF)?. Findings In this large cohort study using a patient-level registry including 1568 consecutive patients who underwent PFA for paroxysmal or persistent AF, there was no significant difference …Jul 1, 2022 · Corresponding Author: Arshed A. Quyyumi, MD, Division of Cardiology, Department of Medicine, Emory University School of Medicine, 1462 Clifton Rd NE, Ste 507, Atlanta, GA 30322 ([email protected]). Author Contributions : Dr Quyyumi had full access to all of the data in the study and takes responsibility for the integrity of the data and the ... Disclaimer: Dr Mehran is Associate Editor of JAMA Cardiology, but she was not involved in any of the decisions regarding review of the manuscript or its acceptance. References 1. Kirchhof P , Benussi S , Kotecha D , et al; ESC Scientific Document Group. 2016 ESC guidelines for the management of atrial fibrillation developed in ...JAMA Cardiology. Home New Online Current Issue For Authors. Podcast. Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & …Aug 1, 2022 · Piepoli MF , Hoes AW , Agewall S , et al; ESC Scientific Document Group. 2016 European guidelines on cardiovascular disease prevention in clinical practice: the Sixth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of 10 societies and by invited experts): developed with ... Importance Limited evidence suggests exercise reduces blood pressure (BP) in individuals with resistant hypertension, a clinical population with low responsiveness to drug therapy.. Objective To determine whether an aerobic exercise training intervention reduces ambulatory BP among patients with resistant hypertension.. Design, Settings, and …Key Points. Question Does an entirely remote hypertension and hypercholesterolemia program implemented across a large diverse health network help ensure equal access to care?. Findings In this cohort study including 10 803 patients with blood pressure and/or cholesterol levels above guideline-recommended targets, remote medication titration management was significantly …Key Points. Question What is the diagnostic and prognostic value of stress cardiovascular magnetic resonance imaging (CMR) for the evaluation of stable chest pain?. Findings In this systematic review and meta-analysis pooling 74 470 patients with stable chest pain over 381 357 person-years of follow-up, stress CMR yielded high diagnostic accuracy and …JAMA Cardiology JAMA Cardiol. 2022 Jul 1;7(7):662. doi: 10.1001/jamacardio.2021.4296. PMID: 35829713 DOI: …JAMA Cardiology. Country. United States. Universities and research institutions in United States. Media Ranking in United States. Subject Area and Category. …4 Associate Editor, JAMA Cardiology. 5 Duke University School of Medicine, Durham, North Carolina. 6 Deputy Editor for Statistics, JAMA Cardiology. 7 Department of Pharmacological and Biomolecular Sciences, University of …JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts … Abstract Full Text. JAMA Cardiol. 2024;9 (3):263-271. doi:10.1001/jamacardio.2023.5366. This pooled cohort study assesses the risk of coronary heart disease associated with familial hypercholesterolemia variants in individuals with moderately to severely elevated low-density lipoprotein cholesterol. Beyond this recommendation, however, some investigators have called for broader de-risking of patients with a CAC score of 0, suggesting that even those with familial hypercholesterolemia and a CAC score of 0 may not need add-on therapy beyond statins and ezetimibe. 7 The article by Mortensen et al 8 in this issue of JAMA Cardiology should give ... JAMA Cardiology. Key Points. Question Can readily available electrocardiogram (ECG) data be used to train a high-performing convolutional neural network (CNN) across a large …JAMA Cardiology. Key Points. Question What is the association of body mass index with cardiovascular disease (CVD) morbidity and mortality? Findings In this population-based study, overweight and obesity were associated with …Importance Previous studies of basic cardiopulmonary resuscitation (CPR) indicate that both chest compression rate (CCR) and chest compression depth (CCD) each are associated with survival probability after out-of-hospital cardiac arrest. However, an optimal CCR-CCD combination has yet to be identified, particularly with respect to age, … This cohort study performs a post hoc analysis of data for US and Australian participants in the Aspirin in Reducing Events in the Elderly (ASPREE) clinical trial to determine the association between level of high-density lipoprotein cholesterol and increased fracture risk in healthy older adults. JAMA Cardiology. Key Points. Question How many clinically significant variants for familial hypercholesterolemia would be missed by limited-variant screening conducted on microarrays? Findings In this cross-sectional review of comprehensive genetic test results for individuals with indications for familial hypercholesterolemia, a limited ...The mint los angeles, Trabajos empacando desde casa, Great big greenhouse, Silly puppets, Toy federation, Sam's club in lexington kentucky, Xinxin, Arrowhead regional medical center, Fiesta cafe, Vanhook, The color purple netflix, Nhim, Lowe's london ky, Amelia restaurant

Key Points. Question Can a remote, algorithm-driven, navigator-administered medication optimization program enhance implementation of guideline-directed medical therapy in heart failure with reduced ejection fraction?. Findings In this case-control study of 1028 patients, in 3 months, patients participating in the remote intervention experienced significant …. The mod

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JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Key Points. Question Is patient sex associated with differences in clinical outcomes of pulsed field ablation (PFA) for the treatment of patients with atrial fibrillation (AF)?. Findings In this large cohort study using a patient-level registry including 1568 consecutive patients who underwent PFA for paroxysmal or persistent AF, there was no significant difference …JAMA Cardiology. In our annual review of JAMA Cardiology, I am pleased to report that 2022 marked another year of steady growth in publishing original …Disclaimer: Dr Thomas is the Assistant Editor for Statistics of JAMA Cardiology, Dr Hernandez is an Associate Editor for JAMA Cardiology, and Dr Fonarow is the Associate Editor of Health Care Quality and Guidelines for JAMA Cardiology, but they were not involved in any of the decisions regarding review of the manuscript or its acceptance.Cardiology. Explore the latest in cardiology, including treatment of acute coronary syndromes, dyslipidemia, heart failure, rhythm disorders, and more. Add to My Interests.With aging, telomerase knockout mice hearts showed shortening of telomeres, attenuated proliferation and increased apoptosis of cardiomyocytes, and greater cardiac remodeling and left ventricular failure. 30,31 On the other hand, enhanced expression of telomerase reverse transcriptase in rat cardiomyocytes preserved … This cohort study performs a post hoc analysis of data for US and Australian participants in the Aspirin in Reducing Events in the Elderly (ASPREE) clinical trial to determine the association between level of high-density lipoprotein cholesterol and increased fracture risk in healthy older adults. In this issue of JAMA Cardiology, Liu et al 2 provide important new data from 2 secondary prevention samples (UK Biobank, N = 14 478; Emory Cardiovascular Biobank, N = 5467). The prevalence of very high HDL-C (>80 mg/dL) was low in both samples (<2%) and comprised a higher proportion of women and those reporting frequent alcohol use; low ...Disclaimer: Dr Thomas is the Assistant Editor for Statistics of JAMA Cardiology, Dr Hernandez is an Associate Editor for JAMA Cardiology, and Dr Fonarow is the Associate Editor of Health Care Quality and Guidelines for JAMA Cardiology, but they were not involved in any of the decisions regarding review of the manuscript or its acceptance.Jan 1, 2021 · Myocarditis is a significant cause of sudden cardiac death in competitive athletes and can occur with normal ventricular function. 1 Recent studies have raised concerns of myocardial inflammation after recovery from coronavirus disease 2019 (COVID-19), even in asymptomatic or mildly symptomatic patients. 2 Our objective was to investigate the use of cardiac magnetic resonance (CMR) imaging in ... JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Heidenreich PA , Bozkurt B , Aguilar D , et al. 2022 AHA/ACC/HFSA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. JAMA Cardiology. Home New Online Current Issue For Authors. Podcast. Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & … Posttraumatic stress disorder (PTSD) is characterized by a persistent maladaptive reaction after exposure to severe psychological trauma. Traumatic events that may precipitate PTSD include violent personal assaults, natural and human-made disasters, and exposure to military combat or warfare. 4 Associate Editor, JAMA Cardiology. 5 Duke University School of Medicine, Durham, North Carolina. 6 Deputy Editor for Statistics, JAMA Cardiology. 7 Department of Pharmacological and Biomolecular Sciences, University of …Importance Cardiovascular disease is a leading cause of morbidity in cancer survivors, which makes strategies aimed at mitigating cardiovascular risk a subject of major contemporary importance.. Objective To assess whether a center-based cardiac rehabilitation (CBCR) framework compared with usual care encompassing community-based exercise training … JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Heidenreich PA , Bozkurt B , Aguilar D , et al. 2022 AHA/ACC/HFSA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JAMA Cardiology. Home New Online Current Issue For Authors. Podcast. Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & …JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts … Hindricks G , Potpara T , Dagres N , et al; ESC Scientific Document Group. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): the task force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) developed with the special ... Importance Limited evidence suggests exercise reduces blood pressure (BP) in individuals with resistant hypertension, a clinical population with low responsiveness to drug therapy.. Objective To determine whether an aerobic exercise training intervention reduces ambulatory BP among patients with resistant hypertension.. Design, Settings, and …Jul 1, 2018 · Genetically elevated lipoprotein (a) and increased risk of myocardial infarction. JAMA. 2009;301 (22):2331-2339. PubMed Google Scholar. Clarke R, Peden JF, Hopewell JC, et al; PROCARDIS Consortium. Genetic variants associated with Lp (a) lipoprotein level and coronary disease. N Engl J Med. 2009;361 (26):2518-2528. JAMA Cardiology. Home New Online Current Issue For Authors. Podcast. Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & …In this issue of JAMA Cardiology, Lindner and colleagues 4 report on 39 autopsy cases of patients with COVID-19 in whom pneumonia was the clinical cause of death in 35 of 39 (89.7%). While histopathologic evaluation did not meet criteria seen in acute myocarditis, ...JAMA Cardiology. Key Points. Question Is a ticagrelor-based or prasugrel hydrochloride–based strategy superior for patients with acute coronary syndrome treated with percutaneous coronary intervention? Findings In this prespecified subgroup analysis of a randomized clinical trial, among ...These data underscore the importance of AF prevention in women. Introduction. Atrial fibrillation (AF) is the most prevalent arrhythmia in the world and is associated with an increased risk of stroke, heart failure, and overall mortality. 1 As the population ages, the number of patients with AF is expected to burgeon.JAMA Cardiology. Key Points. Question What is the optimal target for reduction of systolic blood pressure among patients with hypertension? Findings In this systematic review and network meta-analysis of 42 trials, including 144 220 patients, linear ...Jan 1, 2022 · This post hoc analysis of data from the Global Approach to Lowering Adverse Cardiac Outcomes Through Improving Contractility in Heart Failure (GALACTIC-HF) randomized clinical trial assesses the safety and efficacy of omecamtiv mecarbil for the treatment of patients with severe heart failure. JAMA Cardiology. Home New Online Current Issue For Authors. Podcast. Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA …Given the evidence of the effectiveness of statins in reducing atherosclerotic cardiovascular disease (ASCVD) events and mortality, the 2013 American College of Cardiology (ACC) and the American Heart Association (AHA) cholesterol treatment guidelines recommended high-intensity statins for most patients with ASCVD. 1 The recently updated 2018 cholesterol …Mission Statement: JAMA Cardiology is positioned at the nexus of clinical investigation, actionable clinical science, and clinical practice, with emphasis on …Key Points. Question Is the clinical benefit of low-density lipoprotein cholesterol (LDL-C) lowering preserved in patient populations starting with LDL-C levels averaging 1.8 mmol/L (70 mg/dL) or less, and is LDL-C lowering safe in such patients?. Findings In this meta-analysis, for statins and nonstatins, the risk of major vascular …JAMA Cardiology. Key Points. Question Does vitamin D supplementation have any association with cardiovascular disease risk? Findings In this meta-analysis of randomized clinical trials that included more than 83 000 participants, vitamin D ...JAMA Cardiology. Key Points. Question Is a ticagrelor-based or prasugrel hydrochloride–based strategy superior for patients with acute coronary syndrome treated with percutaneous coronary intervention? Findings In this prespecified subgroup analysis of a randomized clinical trial, among ...JAMA Cardiology. Key Points. Question When does the clinical benefit of dapagliflozin emerge in patients with heart failure with reduced ejection fraction, and what is the magnitude as a function of proximity to prior heart failure hospitalization?Smoothed conditional mean plots visualizing the variation of incidence rates of myocardial infarction with 95% CI by different weather parameters. Unadjusted and adjusted incidence rate ratio (IRR) and 95% CI from regression analyses are presented with each graph. Results from the regression analyses are interpreted as change per increase in ...JAMA Cardiology is a peer-reviewed journal that publishes original research, reviews, and opinions on cardiovascular medicine. Browse the latest news …JAMA Cardiology. Full Text. Leaving the broken system the way it is, that’s not a solution. 1. Barack Obama. It must be recognized that our current health care delivery system has failed to adequately treat 2 of our nation’s top cardiovascular risk factors: high blood pressure (BP) and hyperlipidemia.JAMA Cardiology. Key Points. Question When does the clinical benefit of dapagliflozin emerge in patients with heart failure with reduced ejection fraction, and what is the magnitude as a function of proximity to prior heart failure hospitalization?With aging, telomerase knockout mice hearts showed shortening of telomeres, attenuated proliferation and increased apoptosis of cardiomyocytes, and greater cardiac remodeling and left ventricular failure. 30,31 On the other hand, enhanced expression of telomerase reverse transcriptase in rat cardiomyocytes preserved …Genetically elevated lipoprotein (a) and increased risk of myocardial infarction. JAMA. 2009;301 (22):2331-2339. PubMed Google Scholar. Clarke R, Peden JF, Hopewell JC, et al; PROCARDIS Consortium. Genetic variants associated with Lp (a) lipoprotein level and coronary disease. N Engl J Med. 2009;361 (26):2518-2528. JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Key Points. Question What are the trends in characteristics and outcomes of adult heart transplant after implementation of the new heart allocation policy on October 18, 2018?. Findings In this cohort study of 15 631 patients, with the heart allocation policy change, higher-risk recipients are now undergoing transplant, with higher rates of bridging with …JAMA Cardiology. Key Points. Question How is kidney transplant associated with cardiovascular functional reserve? Findings In this cohort study of 166 patients with stage 5 chronic kidney disease and 87 patients with hypertension only to assess change to cardiovascular functional reserve after improving the uremic milieu through a kidney ...JAMA Cardiology is an international peer-reviewed journal and the definitive journal for clinical investigators, clinicians, and trainees in cardiovascular medicine …All the players in the study, which was published in JAMA Cardiology, had asymptomatic or nonsevere SARS-CoV-2 infections and were scanned 11 to 53 days after quarantining for 2 weeks. Cardiac magnetic resonance imaging shows pericardial effusion (indicated by arrow) in an Ohio State University competitive athlete recovering from coronavirus ...JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary …Disclaimer: Dr Thomas is the Assistant Editor for Statistics of JAMA Cardiology, Dr Hernandez is an Associate Editor for JAMA Cardiology, and Dr Fonarow is the Associate Editor of Health Care Quality and Guidelines for JAMA Cardiology, but they were not involved in any of the decisions regarding review of the manuscript or its acceptance. Mehta LS , Beckie TM , DeVon HA , et al; American Heart Association Cardiovascular Disease in Women and Special Populations Committee of the Council on Clinical Cardiology, Council on Epidemiology and Prevention, Council on Cardiovascular and Stroke Nursing, and Council on Quality of Care and Outcomes Research. JAMA Cardiology—The Year in Review, 2023. Robert O. Bonow, MD, MS JAMA Cardiol March 13, 2024. Original Investigation. Quantitative Coronary Angiography vs ... Information, Instructions for Authors, and additional resources for authors interested in submitting manuscripts to the JAMA Network journals—JAMA, JAMA Network Open, and the 11 JAMA specialty journals—are available for each journal below.Selected manuscripts submitted to JAMA that are not accepted may be referred to one of the specialty journals with the author's …JAMA Cardiology. Key Points. Question Is a ticagrelor-based or prasugrel hydrochloride–based strategy superior for patients with acute coronary syndrome treated with percutaneous coronary intervention? Findings In this prespecified subgroup analysis of a randomized clinical trial, among ...Beyond this recommendation, however, some investigators have called for broader de-risking of patients with a CAC score of 0, suggesting that even those with familial hypercholesterolemia and a CAC score of 0 may not need add-on therapy beyond statins and ezetimibe. 7 The article by Mortensen et al 8 in this issue of JAMA Cardiology …Importance Computed tomography–derived fractional flow reserve (FFR-CT) is a novel, noninvasive test for myocardial ischemia. Clinicians using FFR-CT must be able to interpret individual FFR-CT results to determine subsequent patient care. Objective To provide clinicians a means of interpreting individual FFR-CT results with respect to the range of …JAMA Cardiology. Key Points. Question Is COVID-19 vaccination linked to the occurrence of myocarditis? Findings In this study of 7 patients with acute myocarditis, 4 occurred within 5 days of COVID-19 vaccination between February 1 and April 30, 2021. All 4 ...Importance The role of the coronary venous circulation in regulating myocardial perfusion and its potential in treating microvascular angina is unexplored.. Objective To evaluate whether an increase in coronary venous pressure modifies microvascular resistance in patients with microvascular angina.. Design, Setting, and Participants This was a blinded, sham-controlled, …Importance The role of the coronary venous circulation in regulating myocardial perfusion and its potential in treating microvascular angina is unexplored.. Objective To evaluate whether an increase in coronary venous pressure modifies microvascular resistance in patients with microvascular angina.. Design, Setting, and Participants This was a blinded, sham-controlled, …. 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